An investigation into the detection of three common veterinary pharmaceutic

Summary

unknown

Program

Thoroughbred Horses

Research Organisation

Racing Analytical Services Ltd

Objective Summary

The purpose of this research is to study the absorption distribution metabolism and excretion of 3 therapeutic substances frusemide betamethasone and triamcinolone acetonide commonly used by veterinarians during the preparation of horses for competition in the thoroughbred and standardbred industries as will as in high level equestrian events. Frusemide is a high ceiling diuretic commonly used in the management of exercise induced pulmonary haemorrhage in racehorses. Batemethasone and trimcinoloneacetetonide are corticosteroid drugs used for intraarticular treatment and/or management of horses with degenerative joint disease. Several of the analytical procedures used to detect these drugs in urine samples from competing horses are abut to change. These changes may alter the detection periods of these commonlyused drugs. The proposed project will provide reliable and uptodate drug excretion data for frusemide practising veterinarians in a meaningful number of horses. Pilot studies involvingthe corticosteroid drugs are aimed at providing preliminary data on likely detection periods. This will be a first step in providing information on responsible use of intraarticular corticosteroids which is consistent with animal welfare and the racingindustry's rules on the use of medications in racehorses

Project Code

PRJ-000790

Project Stage

Closed

Project Start Date

Sunday, July 31, 2005

Project Completion Date

Wednesday, January 31, 2007

Journal Articles From Project

Not Available

National Priority

An environmentally sustainable Australia

National Priority

Soil, water and managing natural resources

National Priority

HOR-Reduce the incidence and impact of diseases and parasites in horses

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