The development of horse embryonic stem cells (eESCs)

Summary

unknown

Program

Thoroughbred Horses

Research Organisation

Monash University

Objective Summary

The project aims to develop pluripotential equine embryonic stem cells (eESCs) from morulae blastocysts and by separation and culture of the ICM of the horse blastocyst. This method has been used to derive mouse and primate ESCs that are immortal and capable of differentiation into all the cells of the organism. In addition we propose to derive equine specific eESCs (ESESCs) by the insertion of horse somatic cell nuclei and mitochondria into enucleated mouse or rabbit eggs to isolate eESCs from xenogenic embryos. eESCs cell will be characterised by methods used for mice primate and humans.

Project Code

PRJ-000669

Project Stage

Closed

Project Start Date

Friday, July 1, 2005

Project Completion Date

Wednesday, December 24, 2008

Journal Articles From Project

Not Available

National Priority

Frontier technologies for building and transforming Australian industries

National Priority

Adoption of R&D

National Priority

HOR-Reduce the incidence and impact of diseases and parasites in horses

Contact

Related publications

15.09.10

The Development of Horse Embryonic and Amnion Derived Stem Cells