Summary
unknown
Program
Thoroughbred Horses
Research Organisation
Monash University
Objective Summary
The project aims to develop pluripotential equine embryonic stem cells (eESCs) from morulae blastocysts and by separation and culture of the ICM of the horse blastocyst. This method has been used to derive mouse and primate ESCs that are immortal and capable of differentiation into all the cells of the organism. In addition we propose to derive equine specific eESCs (ESESCs) by the insertion of horse somatic cell nuclei and mitochondria into enucleated mouse or rabbit eggs to isolate eESCs from xenogenic embryos. eESCs cell will be characterised by methods used for mice primate and humans.
Project Code
PRJ-000669
Project Stage
Closed
Project Start Date
Friday, July 1, 2005
Project Completion Date
Wednesday, December 24, 2008
Journal Articles From Project
Not Available
National Priority
Frontier technologies for building and transforming Australian industries
National Priority
Adoption of R&D
National Priority
HOR-Reduce the incidence and impact of diseases and parasites in horses