Mechanistic and Comparative toxicity of Commercial Essential Oils

Summary

The project involves recruitment of a PhD student to work on an experimental program centred on endocrine disruption by essential oils in experimental animals. The student once recruited would review the literature on essential oil endocrine disruption, fertility in the male rat, and differences in their physiology in comparison to other experimental animals and humans. These reviews would lead to publications in appropriate journals. Once the literature has been reviewed the student would develop an experimental program to identify which physiological pathways are disrupted in experimental animals by TTO and other essential oils of similar or overlapping composition. From this work the research project would seek to identify the relevance of male rat infertility from TTO to human health risk assessment.

Program

Tea Tree Oil

Research Organisation

The University of Queensland

Objective Summary

The project objective is to publish reviews and experimental data identifying the mechanisms of Tea Tree Oil and related essential oils production of infertility in male rats and the relevance to human health risk assessment.