Project overview: A strategy to increase demand for retired Thoroughbreds in Australia
The Thoroughbred industry in Australia is the second largest in the world, both in terms of breeding and the number of races held. The industry...
THOROUGHBRED HORSES
The Pharmacokinetics of Equine Medications
115 pages
Published: 20 Jan 2012
Share this content
-
Download report PDF
Download -
Purchase a hard copy - AUD $55.00
This RIRDC report provides information about the pharmacokinetics of 12 equine medications. For each medication, the report illustrates that time taken for the drug to reach its maximum concentration (and hence maximum effectiveness) in the blood, its rate of metabolism and removal from the bloodstream, and the time taken for the drug and its metabolites to be eliminated from the body via the urine.
The report also provides new insights into how metabolite data can be modelled to provide useful information about the behaviour of the parent drug, and how the variation between individual horses can be measured and used to estimate the level of risk of any horse in the population of breaching a detection limit at any given time point after drug administration.
This information should assist veterinarians to develop more effective treatment protocols for horses, and will assist the racing industry regulators in setting appropriate detection times and reporting levels for therapeutic substances in animals that compete.
Related resources
Project overview: AMR equine modules and supporting materials
The requirement for increased antimicrobial stewardship (AMS) across all industries and the knowledge that sub-optimal prescribing occurs in the veterinary industry dictates that work to...
Antimicrobial prescribing guidelines for horses in Australia
Antimicrobials are commonly used to treat equine infections, but complications with therapy are also relatively common. Antimicrobial-associated diarrhoea (Section 6), immune mediated diseases and nephrotoxicity...
Yearling X-ray lesions and the effect on longterm performance in Thoroughbred horses
Radiography is a key part of stakeholder decision-making when buying, selling and managing Thoroughbred yearlings. In Australia, a standard set of radiographs obtained within 42...
Project snapshot: Epidemiological and bacterial analyses of Salmonella infection in the Australian Thoroughbred horse breeding industry
Salmonella is an important intestinal infection of horses of all ages, and can cause colic, diarrhoea, generalised illness and death. Horses infected with Salmonella frequently need intensive treatment...
Epidemiological and bacterial analyses of Salmonella infection in the Australian Thoroughbred horse breeding industry
Salmonella infection can result in major health consequences in horses. The recommendations drawn from this study are crucial for improving biosecurity measures and infection control practices...
Measurement of economic impact of the Australian thoroughbred breeding industry
The Australian thoroughbred breeding industry contributes nearly $1.68 billion annually to the Australian economy and provides full-time employment for over 9,000 people, predominantly in rural...
Project snapshot: Economic impact of the Australian thoroughbred breeding industry
The Australian thoroughbred breeding industry is the second-largest in the world and makes a substantial economic and social contribution to the country. Research capturing the...