Collaborative approach to take the “Query” out of Q fever

22.01.20

Australian scientists and livestock managers are working collaboratively to reduce the incidence of Q Fever outbreaks in Australia which has one of the world’s highest rates of the disease.

The Q Fever Group, funded by the Australian Government Department of Agriculture as part of its Rural R&D for Profit program, with support from AgriFutures Australia and university and industry partners, brings together PhD students along with animal health and infectious disease experts from the University of Melbourne, University of Adelaide, Charles Sturt University, the University of Queensland, the Australian Rickettsial Reference Laboratory, Goat Vet Oz and Meredith Dairy to take the “Query” out of Q fever.

The project aims to improve the understanding of how and why Q fever can spread, recognising the severe risk to human health. This multidisciplinary three-year project will specifically look to understand Q fever reservoirs, amplification and transmission pathways in and outside Australian livestock farms to better understand the factors influencing the risk of Q fever spread within and between Australian livestock enterprises. This will assist the development of national guidelines for an emergency response plan to be used in the event of future Q fever outbreaks in Australia.

Q Fever Group Primary Investigator Professor Mark Stevenson, from the University of Melbourne’s Faculty of Veterinary and Agricultural Science, described the project as a necessary step to ensure we are all better prepared to manage Q Fever disease risk. Our biosecurity practices need to be aligned with the most up-to-date information on Q fever distribution (frequency and pattern) and determinants (cause and risk factors).

”We have some of the highest rates of human infection of Q Fever in the world, and a combination of climatic conditions that favour disease spread and a growing livestock industry makes us susceptible to outbreaks. Internationally, we have seen large-scale Q fever outbreaks resulting in ongoing health issues for infected people and even deaths,” said Professor Stevenson.

“By learning from these historic outbreaks, as well as developing a better understanding of the way Q fever spreads in Australian livestock, we will have the knowledge to better mitigate the risk of such outbreaks and their ramifications for both livestock and public health.”

Project manager Dr Bonny Cumming from the University of Melbourne highlighted the importance of communication and transparency for this project. “Extending the project’s findings to industry and the general public is critical to ensuring our research has tangible and practical benefits for those most impacted. Connecting livestock workers with key information about best practices to improve hygiene and reduce risk of Q fever transmission is a critically important step to help ensure the health and safety of our agricultural industry,” said Dr Cumming.

“Our aim is to ensure that through communicating our research findings, farmers, abattoir workers and other members of the livestock industry will be equipped with the necessary knowledge and resources to better protect themselves and their families from Q fever and its potentially debilitating consequences.”

Q fever is an infectious disease of humans and animals caused by the bacteria Coxiella burnetii. In humans, Q fever infection can cause a prolonged, debilitating illness. A small proportion of affected individuals develop ongoing, chronic syndromes that include pneumonia and inflammation of the inner chambers of the heart (endocarditis).

Intensively managed livestock are the primary sources of human infection in Australia. Sheep, goats and cattle can all provide conditions favourable for the amplification and spread of Q fever. Coxiella burnetii is one of the most contagious organisms known to man, a single organism is sufficient to cause infection. This means that a number of transmission pathways exist, with the most common routes of infection being inhalation of contaminated dust, contact with contaminated milk, meat, wool and close contact with infected animals, particularly their birthing products.

In the Netherlands during 2007-2010 there was a large outbreak of Q fever in humans, with 4000 confirmed cases and 30 deaths. More recently and closer to home in Australia, at least 24 people contracted Q fever on a property west of Ballarat. Dairy goat herds, infected with Q fever, were the source of both outbreaks. There is the risk that an extensive outbreak of Q fever, similar to what occurred in the Netherlands, could occur in Australia. The Q Fever project team is working closely with its government partners to provide research for policy development that will limit the likelihood of a large and prolonged Q fever outbreak in Australia. This will not only help to protect Australian residents from the spread of the disease, it will also help to maintain Australia’s position as an exporter of premium agricultural produce.

To keep up with our findings go to https://fvas.unimelb.edu.au/research/areas/animal-welfare-and-veterinary-sciences/taking-the-query-out-of-q-fever#about) and follow us on Facebook (https://www.facebook.com/QFeverGroup/) or Twitter (@Qfever_Group).

This project is supported by AgriFutures Australia through funding from the Australian Government Department of Agriculture as part of its Rural R&D for Profit program.

 

Media Enquiries:

Lauren Sharkey, AgriFutures Australia, Manager, Communications & Capacity Building

lauren.sharkey@agrifutures.com.au | 02 6923 6916 | 0409 966 182